Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50088774
Substrate
n/a
Meas. Tech.
ChEBML_45057
Ki
35±n/a nM
Citation
 Scozzafava, A; Mastrolorenzo, A; Supuran, CT Arylsulfonyl-N,N-diethyl-dithiocarbamates: a novel class of antitumor agents. Bioorg Med Chem Lett 10:1887-91 (2000) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50088774
Synonyms:
4-(2-{[(morpholin-4-ylcarbonothioyl)thio]amino}ethyl)benzenesulfonamide | CHEMBL13975 | N,N-dialkylthio-carbonylsulfenylamino derivative
Type:
Small organic molecule
Emp. Form.:
C13H19N3O3S3
Mol. Mass.:
361.503
SMILES:
NS(=O)(=O)c1ccc(CCNSC(=S)N2CCOCC2)cc1
Structure:
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