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Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM50237949
Substrate
n/a
Meas. Tech.
ChEMBL_1931297 (CHEMBL4434548)
IC50
13300±n/a nM
Citation
 Tasker, NR; Rastelli, EJ; Burnett, JC; Sharlow, ER; Lazo, JS; Wipf, P Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett 29:2008-2015 (2019) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM50237949
Synonyms:
2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid | CHEMBL398538
Type:
Small organic molecule
Emp. Form.:
C15H9NO4S2
Mol. Mass.:
331.366
SMILES:
OC(=O)c1ccccc1-c1ccc(C=C2SC(S)=NC2=O)o1 |w:13.13,c:18|
Structure:
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