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Target
Protein tyrosine phosphatase type IVA 1
Ligand
BDBM396097
Substrate
n/a
Meas. Tech.
ChEMBL_1931303 (CHEMBL4434554)
IC50
50±n/a nM
Citation
 Tasker, NR; Rastelli, EJ; Burnett, JC; Sharlow, ER; Lazo, JS; Wipf, P Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett 29:2008-2015 (2019) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 1
Synonyms:
PRL1 | PTP4A1 | PTPCAAX1 | TP4A1_HUMAN
Type:
PROTEIN
Mol. Mass.:
19823.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461024
Residue:
173
Sequence:
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
  
Inhibitor
Name:
BDBM396097
Synonyms:
US10308663, JMS-631-053
Type:
Small organic molecule
Emp. Form.:
C13H8N2O2S
Mol. Mass.:
256.28
SMILES:
N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1
Structure:
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