Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50537898
Substrate
n/a
Meas. Tech.
ChEMBL_1971675 (CHEMBL4604493)
IC50
59000±n/a nM
Citation
 Bae, J; Cho, E; Park, JS; Won, TH; Seo, SY; Oh, DC; Oh, KB; Shin, J Isocadiolides A-H: Polybrominated Aromatics from a  J Nat Prod 83:429-437 (2020) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50537898
Synonyms:
Cadiolide C
Type:
Small organic molecule
Emp. Form.:
C24H12Br4O6
Mol. Mass.:
715.964
SMILES:
Oc1ccc(\C=C2/OC(=O)C(C(=O)c3cc(Br)c(O)c(Br)c3)=C2c2ccc(O)c(Br)c2)cc1Br |c:22|
Structure:
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