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Target
Cyclin-C
Ligand
BDBM50540076
Substrate
n/a
Meas. Tech.
ChEMBL_1980147 (CHEMBL4613409)
Kd
10.0±n/a nM
Citation
 Cheng, W; Yang, Z; Wang, S; Li, Y; Wei, H; Tian, X; Kan, Q Recent development of CDK inhibitors: An overview of CDK/inhibitor co-crystal structures. Eur J Med Chem 164:615-639 (2019) [PubMed]  Article 
Target
Name:
Cyclin-C
Synonyms:
CCNC | CCNC_HUMAN | Cyclin C | SRB11 homolog | hSRB11
Type:
PROTEIN
Mol. Mass.:
33244.88
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107900
Residue:
283
Sequence:
MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
  
Inhibitor
Name:
BDBM50540076
Synonyms:
CHEMBL4649097
Type:
Small organic molecule
Emp. Form.:
C23H35N5O3
Mol. Mass.:
429.5557
SMILES:
Cc1ccc(cc1)-n1nc(cc1NC(=O)NCCCNC(=O)OC(C)(C)C)C(C)(C)C
Structure:
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