Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50541138
Substrate
n/a
Meas. Tech.
ChEMBL_1983770 (CHEMBL4617176)
Ki
4.2±n/a nM
Citation
 Perry, CK; Casey, AB; Felsing, DE; Vemula, R; Zaka, M; Herrington, NB; Cui, M; Kellogg, GE; Canal, CE; Booth, RG Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50541138
Synonyms:
CHEMBL4641654
Type:
Small organic molecule
Emp. Form.:
C18H20ClN
Mol. Mass.:
285.811
SMILES:
CN(C)C1CCc2c(C1)cccc2-c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: