Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50097792
Substrate
n/a
Meas. Tech.
ChEBML_209600
Ki
10000±n/a nM
Citation
 Juteau, H; Gareau, Y; Labelle, M; Lamontagne, S; Tremblay, N; Carrière, MC; Sawyer, N; Denis, D; Metters, KM Structure-activity relationship on the human EP3 prostanoid receptor by use of solid-support chemistry. Bioorg Med Chem Lett 11:747-9 (2001) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50097792
Synonyms:
(E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic acid | 3-(2-(naphthalen-2-ylmethyl)phenyl)acrylic acid | CHEMBL423815
Type:
Small organic molecule
Emp. Form.:
C20H16O2
Mol. Mass.:
288.3398
SMILES:
OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1
Structure:
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