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Target
Prostacyclin receptor
Ligand
BDBM50097794
Substrate
n/a
Meas. Tech.
ChEBML_158465
Ki
>76000±n/a nM
Citation
 Juteau, H; Gareau, Y; Labelle, M; Lamontagne, S; Tremblay, N; Carrière, MC; Sawyer, N; Denis, D; Metters, KM Structure-activity relationship on the human EP3 prostanoid receptor by use of solid-support chemistry. Bioorg Med Chem Lett 11:747-9 (2001) [PubMed]  Article 
Target
Name:
Prostacyclin receptor
Synonyms:
PGI receptor | PI2R_HUMAN | PRIPR | PTGIR | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor | Prostanoid IP receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40968.22
Organism:
Homo sapiens (Human)
Description:
The membranes prepared from human platelet were used in binding assay.
Residue:
386
Sequence:
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
  
Inhibitor
Name:
BDBM50097794
Synonyms:
(E)-3-[2-(4-Methylsulfanyl-benzyl)-phenyl]-acrylic acid | CHEMBL165010
Type:
Small organic molecule
Emp. Form.:
C17H16O2S
Mol. Mass.:
284.373
SMILES:
CSc1ccc(Cc2ccccc2\C=C\C(O)=O)cc1
Structure:
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