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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50097891
Substrate
n/a
Meas. Tech.
ChEBML_2818
Ki
140±n/a nM
Citation
 Laban, U; Kurrasch-Orbaugh, D; Marona-Lewicka, D; Nichols, DE A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties. Bioorg Med Chem Lett 11:793-5 (2001) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:
Enzyme
Mol. Mass.:
51935.10
Organism:
Rattus norvegicus (Rat)
Description:
P08909
Residue:
460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM50097891
Synonyms:
4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CHEMBL352186
Type:
Small organic molecule
Emp. Form.:
C15H19FN2O
Mol. Mass.:
262.3226
SMILES:
COc1ccc2[nH]cc(CCN3CCCC3)c2c1F
Structure:
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