Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50541730
Substrate
n/a
Meas. Tech.
ChEMBL_1985283 (CHEMBL4618689)
Ki
159±n/a nM
Citation
 Mugnaini, C; Kostrzewa, M; Bryk, M; Mahmoud, AM; Brizzi, A; Lamponi, S; Giorgi, G; Ferlenghi, F; Vacondio, F; Maccioni, P; Colombo, G; Mor, M; Starowicz, K; Di Marzo, V; Ligresti, A; Corelli, F Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3- J Med Chem 63:7369-7391 (2020) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50541730
Synonyms:
CHEMBL4641784
Type:
Small organic molecule
Emp. Form.:
C22H30N4O4
Mol. Mass.:
414.498
SMILES:
CCCn1c2cn(CCO)nc2c(O)c(C(=O)NC23CC4CC(CC(C4)C2)C3)c1=O |TLB:21:22:20.19.25:26,THB:21:20:27.22.23:26,23:22:19:25.24.26,23:24:27.22.21:19|
Structure:
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