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Target
Cathepsin G
Ligand
BDBM50101131
Substrate
n/a
Meas. Tech.
ChEBML_45338
IC50
2.3±n/a nM
Citation
 Aoyama, Y; Uenaka, M; Konoike, T; Hayasaki-Kajiwara, Y; Naya, N; Nakajima, M Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones. Bioorg Med Chem Lett 11:1691-4 (2001) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50101131
Synonyms:
1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL296771
Type:
Small organic molecule
Emp. Form.:
C16H14N2O2
Mol. Mass.:
266.2946
SMILES:
Cc1ccc(cc1)N1C(=O)N(C1=O)c1ccc(C)cc1
Structure:
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