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Target
Myeloblastin
Ligand
BDBM50544646
Substrate
n/a
Meas. Tech.
ChEMBL_1993415 (CHEMBL4627150)
Ki
26500±n/a nM
Citation
 Kahler, JP; Lenders, S; van de Plassche, MAT; Verhelst, SHL Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction. ACS Med Chem Lett 11:1739-1744 (2020) [PubMed]  Article 
Target
Name:
Myeloblastin
Synonyms:
Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN
Type:
PROTEIN
Mol. Mass.:
27816.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463425
Residue:
256
Sequence:
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP
  
Inhibitor
Name:
BDBM50544646
Synonyms:
CHEMBL4635621
Type:
Small organic molecule
Emp. Form.:
C24H26NO4P
Mol. Mass.:
423.4413
SMILES:
CC(C)C(NC(=O)OCc1ccccc1)P(=O)(Oc1ccccc1)c1ccccc1
Structure:
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