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Target
D(1A) dopamine receptor
Ligand
BDBM50545202
Substrate
n/a
Meas. Tech.
ChEMBL_1994485 (CHEMBL4628380)
Ki
536±n/a nM
Citation
 Karki, A; Juarez, R; Namballa, HK; Alberts, I; Harding, WW Identification of C10 nitrogen-containing aporphines with dopamine D Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50545202
Synonyms:
CHEMBL4638749
Type:
Small organic molecule
Emp. Form.:
C21H20N2O4
Mol. Mass.:
364.3945
SMILES:
COc1cc2CCN(C)C3Cc4ccc(cc4-c(c1OCC#C)c23)[N+]([O-])=O
Structure:
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