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Target
Glucose-6-phosphatase catalytic subunit 1
Ligand
BDBM50103118
Substrate
n/a
Meas. Tech.
ChEBML_71686
IC50
170±n/a nM
Citation
 Madsen, P; Jakobsen, P; Westergaard, N N,N-dibenzyl-N'-benzylidenehydrazines: potent competitive glucose-6-phosphatase catalytic enzyme inhibitors. Bioorg Med Chem Lett 11:2165-7 (2001) [PubMed]  Article 
Target
Name:
Glucose-6-phosphatase catalytic subunit 1
Synonyms:
G6PC | G6PC1 | G6PC1_HUMAN | G6PT | Glucose-6-phosphatase
Type:
PROTEIN
Mol. Mass.:
40493.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_501266
Residue:
357
Sequence:
MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEKAQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIVASLVLLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVIPYCLAQVLGQPHKKSL
  
Inhibitor
Name:
BDBM50103118
Synonyms:
CHEMBL66059 | N,N-Dibenzyl-N'-[1-(5-chloro-thiophen-2-yl)-meth-(E)-ylidene]-hydrazine
Type:
Small organic molecule
Emp. Form.:
C19H17ClN2S
Mol. Mass.:
340.87
SMILES:
Clc1ccc(\C=N\N(Cc2ccccc2)Cc2ccccc2)s1
Structure:
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