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Target
Mitochondrial 2-oxodicarboxylate carrier
Ligand
BDBM50028197
Substrate
n/a
Meas. Tech.
ChEMBL_2015975 (CHEMBL4669553)
IC50
252000±n/a nM
Citation
 Schultz, CR; Gruhlke, MCH; Slusarenko, AJ; Bachmann, AS Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells. J Nat Prod 83:2518-2527 (2020) [PubMed] 
Target
Name:
Mitochondrial 2-oxodicarboxylate carrier
Synonyms:
Mitochondrial 2-oxodicarboxylate carrier | ODC | ODC_HUMAN | SLC25A21 | Solute carrier family 25 member 21
Type:
PROTEIN
Mol. Mass.:
33315.79
Organism:
Homo sapiens
Description:
ChEMBL_120108
Residue:
299
Sequence:
MSAKPEVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW
  
Inhibitor
Name:
BDBM50028197
Synonyms:
2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNITHINE
Type:
Small organic molecule
Emp. Form.:
C6H12F2N2O2
Mol. Mass.:
182.1685
SMILES:
NCCCC(N)(C(F)F)C(O)=O
Structure:
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