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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50546867
Substrate
n/a
Meas. Tech.
ChEMBL_2016850 (CHEMBL4670428)
EC50
6300±n/a nM
Citation
 Hinnah, K; Willems, S; Morstein, J; Heering, J; Hartrampf, FWW; Broichhagen, J; Leippe, P; Merk, D; Trauner, D Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor ? (PPAR?). J Med Chem 63:10908-10920 (2020) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50546867
Synonyms:
CHEMBL4756972
Type:
Small organic molecule
Emp. Form.:
C16H13N3O2S
Mol. Mass.:
311.358
SMILES:
O=C1NC(=O)C(Cc2ccc(cc2)\N=N/c2ccccc2)S1
Structure:
Search PDB for entries with ligand similarity: