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Target
Proto-oncogene tyrosine-protein kinase Src
Ligand
BDBM4531
Substrate
n/a
Meas. Tech.
ChEMBL_202619 (CHEMBL805364)
IC50
4±n/a nM
Citation
 Zhang, N; Wu, B; Wissner, A; Powell, DW; Rabindran, SK; Kohler, C; Boschelli, F 4-Anilino-3-cyanobenzo[g]quinolines as kinase inhibitors. Bioorg Med Chem Lett 12:423-5 (2002) [PubMed]  Article 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src
Synonyms:
Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src
Type:
Protein
Mol. Mass.:
59838.60
Organism:
Homo sapiens (Human)
Description:
P12931
Residue:
536
Sequence:
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM4531
Synonyms:
4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | 4-[(4-Chloro-5-methoxy-2-methylphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile | 4-[(4-chloro-5-methoxy-2-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile | CHEMBL127331
Type:
Small organic molecule
Emp. Form.:
C20H18ClN3O3
Mol. Mass.:
383.828
SMILES:
COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(C)cc1Cl
Structure:
Search PDB for entries with ligand similarity: