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Target
SNF-related serine/threonine-protein kinase
Ligand
BDBM50550129
Substrate
n/a
Meas. Tech.
ChEMBL_2026443 (CHEMBL4680601)
IC50
>10000±n/a nM
Citation
 Wang, CB; Lorente-Macías, Á; Wells, C; Pickett, JE; Picado, A; Zuercher, WJ; Axtman, AD Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series. RSC Med Chem 12:129-136 (2021) [PubMed]  Article 
Target
Name:
SNF-related serine/threonine-protein kinase
Synonyms:
KIAA0096 | SNF1-related kinase | SNFRK | SNRK | SNRK_HUMAN
Type:
PROTEIN
Mol. Mass.:
84281.84
Organism:
Homo sapiens (Human)
Description:
ChEMBL_774232
Residue:
765
Sequence:
MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQDLEDDLTATPLSHATVPQSPARAADSVLNGHRSKGLCDSAKKDDLPELAGPALSTVPPASLKPTASGRKCLFRVEEDEEEDEEDKKPMSLSTQVVLRRKPSVTNRLTSRKSAPVLNQIFEEGESDDEFDMDENLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSDDDSESRRRLDKDSGFTYSWHRRDSSEGPPGSEGDGGGQSKPSNASGGVDKASPSENNAGGGSPSSGSGGNPTNTSGTTRRCAGPSNSMQLASRSAGELVESLKLMSLCLGSQLHGSTKYIIDPQNGLSFSSVKVQEKSTWKMCISSTGNAGQVPAVGGIKFFSDHMADTTTELERIKSKNLKNNVLQLPLCEKTISVNIQRNPKEGLLCASSPASCCHVI
  
Inhibitor
Name:
BDBM50550129
Synonyms:
CHEMBL4744511
Type:
Small organic molecule
Emp. Form.:
C18H16N2O2
Mol. Mass.:
292.3318
SMILES:
COc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Structure:
Search PDB for entries with ligand similarity: