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Target
Prostate-specific antigen
Ligand
BDBM50551469
Substrate
n/a
Meas. Tech.
ChEMBL_2031519 (CHEMBL4685677)
IC50
430±n/a nM
Citation
 Tang, Q; Fu, W; Zhang, M; Wang, E; Shan, L; Chai, X; Pang, J; Wang, X; Xu, X; Xu, L; Li, D; Sheng, R; Hou, T Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation. Eur J Med Chem 192:0 (2020) [PubMed]  Article 
Target
Name:
Prostate-specific antigen
Synonyms:
APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin
Type:
PROTEIN
Mol. Mass.:
28747.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_959198
Residue:
261
Sequence:
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
  
Inhibitor
Name:
BDBM50551469
Synonyms:
CHEMBL4760141
Type:
Small organic molecule
Emp. Form.:
C22H18BrN
Mol. Mass.:
376.289
SMILES:
Brc1ccc(cc1)C1Nc2ccc3ccccc3c2C2C=CCC12 |c:23|
Structure:
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