Reaction Details Report a problem with these data
Target
Platelet glycoprotein VI
Ligand
BDBM50552055
Substrate
n/a
Meas. Tech.
ChEMBL_2033131 (CHEMBL4687289)
Kd
850000±n/a nM
Citation
 Foster, H; Wilson, C; Philippou, H; Foster, R Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. J Med Chem 63:12213-12242 (2020) [PubMed]  Article 
Target
Name:
Platelet glycoprotein VI
Synonyms:
GP6 | GPVI | GPVI_HUMAN | Glycoprotein 6 | Platelet glycoprotein VI
Type:
PROTEIN
Mol. Mass.:
36878.67
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109099
Residue:
339
Sequence:
MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRHRGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS
  
Inhibitor
Name:
BDBM50552055
Synonyms:
CHEMBL4751401
Type:
Small organic molecule
Emp. Form.:
C23H22N4O
Mol. Mass.:
370.447
SMILES:
C(CCc1ccccc1)COc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
Structure:
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