Reaction Details Report a problem with these data
Target
Platelet glycoprotein VI
Ligand
BDBM50396073
Substrate
n/a
Meas. Tech.
ChEMBL_2033133 (CHEMBL4687291)
IC50
48±n/a nM
Citation
 Foster, H; Wilson, C; Philippou, H; Foster, R Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. J Med Chem 63:12213-12242 (2020) [PubMed]  Article 
Target
Name:
Platelet glycoprotein VI
Synonyms:
GP6 | GPVI | GPVI_HUMAN | Glycoprotein 6 | Platelet glycoprotein VI
Type:
PROTEIN
Mol. Mass.:
36878.67
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109099
Residue:
339
Sequence:
MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRKRLRHRGRAVQRPLPPLPPLPLTRKSNGGQDGGRQDVHSRGLCS
  
Inhibitor
Name:
BDBM50396073
Synonyms:
CHEMBL1235110
Type:
Small organic molecule
Emp. Form.:
C18H24N6O
Mol. Mass.:
340.4228
SMILES:
Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)c1 |r|
Structure:
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