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Target
Ribosyldihydronicotinamide dehydrogenase [quinone]
Ligand
BDBM50112204
Substrate
n/a
Meas. Tech.
ChEMBL_104942 (CHEMBL713109)
Ki
70±n/a nM
Citation
 Leclerc, V; Yous, S; Delagrange, P; Boutin, JA; Renard, P; Lesieur, D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed]  Article 
Target
Name:
Ribosyldihydronicotinamide dehydrogenase [quinone]
Synonyms:
Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone]
Type:
Protein
Mol. Mass.:
25917.25
Organism:
Homo sapiens (Human)
Description:
P16083
Residue:
231
Sequence:
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
  
Inhibitor
Name:
BDBM50112204
Synonyms:
CHEMBL52755 | N-[2-(2-Iodo-5-methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C13H14IN3O4
Mol. Mass.:
403.1724
SMILES:
COc1cc2c(CCNC(C)=O)c(I)[nH]c2cc1[N+]([O-])=O
Structure:
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