Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50112495
Substrate
n/a
Meas. Tech.
ChEBML_212328
Ki
50±n/a nM
Citation
 Wu, S; Guilford, WJ; Chou, YL; Griedel, BD; Liang, A; Sakata, S; Shaw, KJ; Trinh, L; Xu, W; Zhao, Z; Morrissey, MM Design and synthesis of aminophenol-based factor Xa inhibitors. Bioorg Med Chem Lett 12:1307-10 (2002) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50112495
Synonyms:
3-(3-{4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-trifluoromethyl-phenylamino}-propenyl)-benzamidine | CHEMBL26500
Type:
Small organic molecule
Emp. Form.:
C24H28F3N5O
Mol. Mass.:
459.5072
SMILES:
CC(=N)N1CCC(CC1)Oc1ccc(NC\C=C\c2cccc(c2)C(N)=N)cc1C(F)(F)F
Structure:
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