Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50554584
Substrate
n/a
Meas. Tech.
ChEMBL_2050015 (CHEMBL4704714)
EC50
>100000±n/a nM
Citation
 Xu, F; Zhao, Y; Zhou, H; Li, C; Zhang, X; Hou, T; Qu, L; Wei, L; Wang, J; Liu, Y; Liang, X Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50554584
Synonyms:
CHEMBL4744260
Type:
Small organic molecule
Emp. Form.:
C19H15F3N2O2S
Mol. Mass.:
392.395
SMILES:
Nc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: