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Target
Histone deacetylase 2b
Ligand
BDBM50115648
Substrate
n/a
Meas. Tech.
ChEMBL_87872 (CHEMBL697294)
IC50
250±n/a nM
Citation
 Wittich, S; Scherf, H; Xie, C; Brosch, G; Loidl, P; Gerhäuser, C; Jung, M Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. J Med Chem 45:3296-309 (2002) [PubMed]  Article 
Target
Name:
Histone deacetylase 2b
Synonyms:
Histone deacetylase HD2
Type:
PROTEIN
Mol. Mass.:
30785.07
Organism:
Zea mays
Description:
ChEMBL_87549
Residue:
286
Sequence:
MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVEKHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQNNEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEMSEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSEQSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
  
Inhibitor
Name:
BDBM50115648
Synonyms:
2-(7-Hydroxycarbamoyl-heptanoylamino)-3-(4-methoxy-phenyl)-propionic acid methyl ester | CHEMBL323695
Type:
Small organic molecule
Emp. Form.:
C19H28N2O6
Mol. Mass.:
380.4354
SMILES:
COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)CCCCCCC(=O)NO
Structure:
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