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Target
Delta-type opioid receptor
Ligand
BDBM50117261
Substrate
n/a
Meas. Tech.
ChEMBL_145612 (CHEMBL754332)
Ki
2±n/a nM
Citation
 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands. J Med Chem 45:3746-54 (2002) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50117261
Synonyms:
12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid | CHEMBL122321
Type:
Small organic molecule
Emp. Form.:
C26H31N5O7S
Mol. Mass.:
557.619
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O
Structure:
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