Reaction Details Report a problem with these data
Target
G-protein coupled receptor 52
Ligand
BDBM50556699
Substrate
n/a
Meas. Tech.
ChEMBL_2056940 (CHEMBL4711941)
IC50
1640±n/a nM
Citation
 Wang, C; Zhang, YF; Guo, S; Zhao, Q; Zeng, Y; Xie, Z; Xie, X; Lu, B; Hu, Y GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes. J Med Chem 64:941-957 (2021) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 52
Synonyms:
GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52
Type:
PROTEIN
Mol. Mass.:
41366.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108391
Residue:
361
Sequence:
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
  
Inhibitor
Name:
BDBM50556699
Synonyms:
CHEMBL4746541
Type:
Small organic molecule
Emp. Form.:
C17H15BrO
Mol. Mass.:
315.204
SMILES:
Brc1ccccc1CC\C=C\C(=O)c1ccccc1
Structure:
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