Reaction Details Report a problem with these data
Target
G-protein coupled receptor 52
Ligand
BDBM50556722
Substrate
n/a
Meas. Tech.
ChEMBL_2056940 (CHEMBL4711941)
IC50
1810±n/a nM
Citation
 Wang, C; Zhang, YF; Guo, S; Zhao, Q; Zeng, Y; Xie, Z; Xie, X; Lu, B; Hu, Y GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes. J Med Chem 64:941-957 (2021) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 52
Synonyms:
GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52
Type:
PROTEIN
Mol. Mass.:
41366.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108391
Residue:
361
Sequence:
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
  
Inhibitor
Name:
BDBM50556722
Synonyms:
CHEMBL4791780
Type:
Small organic molecule
Emp. Form.:
C16H15NO
Mol. Mass.:
237.2964
SMILES:
O=C(\C=C\CCc1ccccc1)c1ccncc1
Structure:
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