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Target
G-protein coupled receptor 84
Ligand
BDBM50556779
Substrate
n/a
Meas. Tech.
ChEMBL_2057182 (CHEMBL4712183)
IC50
0.900000±n/a nM
Citation
 Chen, LH; Zhang, Q; Xie, X; Nan, FJ Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists. J Med Chem 63:15399-15409 (2020) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50556779
Synonyms:
CHEMBL3715656
Type:
Small organic molecule
Emp. Form.:
C26H25N3O4
Mol. Mass.:
443.4944
SMILES:
O=c1nc(OCC2COCCO2)cc2-c3ccc(cc3CCn12)C#CCNc1ccccc1
Structure:
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