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Target
Insulin-like growth factor-binding protein 5
Ligand
BDBM50121965
Substrate
n/a
Meas. Tech.
ChEMBL_90408 (CHEMBL698363)
Kd
718000±n/a nM
Citation
 Kamionka, M; Rehm, T; Beisel, HG; Lang, K; Engh, RA; Holak, TA In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction. J Med Chem 45:5655-60 (2002) [PubMed]  Article 
Target
Name:
Insulin-like growth factor-binding protein 5
Synonyms:
IBP5 | IBP5_HUMAN | IGFBP5 | Insulin-like growth factor binding protein 5
Type:
PROTEIN
Mol. Mass.:
30581.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_90411
Residue:
272
Sequence:
MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
  
Inhibitor
Name:
BDBM50121965
Synonyms:
3-(4-tert-Butoxy-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid | CHEMBL152324
Type:
Small organic molecule
Emp. Form.:
C28H29NO5
Mol. Mass.:
459.5336
SMILES:
CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1
Structure:
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