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Target
Insulin-like growth factor-binding protein 5
Ligand
BDBM50121969
Substrate
n/a
Meas. Tech.
ChEMBL_90408 (CHEMBL698363)
Kd
1075000±n/a nM
Citation
 Kamionka, M; Rehm, T; Beisel, HG; Lang, K; Engh, RA; Holak, TA In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction. J Med Chem 45:5655-60 (2002) [PubMed]  Article 
Target
Name:
Insulin-like growth factor-binding protein 5
Synonyms:
IBP5 | IBP5_HUMAN | IGFBP5 | Insulin-like growth factor binding protein 5
Type:
PROTEIN
Mol. Mass.:
30581.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_90411
Residue:
272
Sequence:
MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
  
Inhibitor
Name:
BDBM50121969
Synonyms:
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid | CHEMBL348015 | DCSD 002855 (1)
Type:
Small organic molecule
Emp. Form.:
C24H21NO4
Mol. Mass.:
387.4278
SMILES:
OC(=O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Structure:
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