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Target
Insulin-like growth factor-binding protein 5
Ligand
BDBM50121966
Substrate
n/a
Meas. Tech.
ChEMBL_90423 (CHEMBL698180)
Kd
1720000±n/a nM
Citation
 Kamionka, M; Rehm, T; Beisel, HG; Lang, K; Engh, RA; Holak, TA In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction. J Med Chem 45:5655-60 (2002) [PubMed]  Article 
Target
Name:
Insulin-like growth factor-binding protein 5
Synonyms:
IBP5 | IBP5_HUMAN | IGFBP5 | Insulin-like growth factor binding protein 5
Type:
PROTEIN
Mol. Mass.:
30581.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_90411
Residue:
272
Sequence:
MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
  
Inhibitor
Name:
BDBM50121966
Synonyms:
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosphonooxy-phenyl)-propionic acid | CHEMBL154506
Type:
Small organic molecule
Emp. Form.:
C24H22NO8P
Mol. Mass.:
483.4071
SMILES:
OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Structure:
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