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Target
Beta-galactoside alpha-2,6-sialyltransferase 1
Ligand
BDBM50559953
Substrate
n/a
Meas. Tech.
ChEMBL_2070763 (CHEMBL4726297)
Ki
55500±n/a nM
Citation
 Montgomery, AP; Dobie, C; Szabo, R; Hallam, L; Ranson, M; Yu, H; Skropeta, D Design, synthesis and evaluation of carbamate-linked uridyl-based inhibitors of human ST6Gal I. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Beta-galactoside alpha-2,6-sialyltransferase 1
Synonyms:
Alpha 2,6-ST 1 | B-cell antigen CD75 | Beta-galactoside alpha-2,6-sialyltransferase 1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 | SIAT1 | SIAT1_HUMAN | ST6GAL1 | ST6Gal I | ST6GalI | Sialyltransferase 1
Type:
PROTEIN
Mol. Mass.:
46622.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109837
Residue:
406
Sequence:
MIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC
  
Inhibitor
Name:
BDBM50559953
Synonyms:
CHEMBL4757654
Type:
Small organic molecule
Emp. Form.:
C22H26N3Na2O11P
Mol. Mass.:
585.4086
SMILES:
n/a
Structure:
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