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Target
Chemerin-like receptor 1
Ligand
BDBM50560506
Substrate
n/a
Meas. Tech.
ChEMBL_2072271 (CHEMBL4727805)
IC50
26±n/a nM
Citation
 Imaizumi, T; Otsubo, S; Komai, M; Takada, H; Maemoto, M; Kobayashi, A; Otsubo, N The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Chemerin-like receptor 1
Synonyms:
CHEMR23 | CHEMR23 | CMKLR1 | CML1_HUMAN | Chemokine-like receptor 1 | DEZ | G-protein coupled receptor ChemR23 | G-protein coupled receptor DEZ
Type:
PROTEIN
Mol. Mass.:
42333.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_100822
Residue:
373
Sequence:
MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML
  
Inhibitor
Name:
BDBM50560506
Synonyms:
CHEMBL4791896
Type:
Small organic molecule
Emp. Form.:
C30H33N7O3
Mol. Mass.:
539.6281
SMILES:
CCCCN([C@H](C)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2c(cccc2o1)C(=O)N(C)CCO |r|
Structure:
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