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Target
Chemerin-like receptor 1
Ligand
BDBM50560539
Substrate
n/a
Meas. Tech.
ChEMBL_2072271 (CHEMBL4727805)
IC50
3.2±n/a nM
Citation
 Imaizumi, T; Otsubo, S; Komai, M; Takada, H; Maemoto, M; Kobayashi, A; Otsubo, N The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Chemerin-like receptor 1
Synonyms:
CHEMR23 | CHEMR23 | CMKLR1 | CML1_HUMAN | Chemokine-like receptor 1 | DEZ | G-protein coupled receptor ChemR23 | G-protein coupled receptor DEZ
Type:
PROTEIN
Mol. Mass.:
42333.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_100822
Residue:
373
Sequence:
MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML
  
Inhibitor
Name:
BDBM50560539
Synonyms:
CHEMBL4783675
Type:
Small organic molecule
Emp. Form.:
C29H26N4O5
Mol. Mass.:
510.5405
SMILES:
C[C@@H](N(CC1CC1)c1nc2c(cccc2o1)C(O)=O)c1ccc(cc1)-c1cc(C)ccc1-c1nc(=O)o[nH]1 |r|
Structure:
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