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Target
Estrogen receptor beta
Ligand
BDBM50561302
Substrate
n/a
Meas. Tech.
ChEMBL_2074718 (CHEMBL4730252)
EC50
0.029000±n/a nM
Citation
 Wetzel, EA; Hanson, AM; Troutfetter, CL; Burkett, DJ; Sem, DS; Donaldson, WA Synthesis and evaluation of 17?-triazolyl and 9?-cyano derivatives of estradiol. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM50561302
Synonyms:
CHEMBL4782490
Type:
Small organic molecule
Emp. Form.:
C19H23NO2
Mol. Mass.:
297.3914
SMILES:
[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1(C#N)c3ccc(O)cc3CC[C@@]21[H] |r|
Structure:
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