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Target
Galectin-1
Ligand
BDBM31592
Substrate
n/a
Meas. Tech.
ChEMBL_2074897 (CHEMBL4730431)
Kd
>500000±n/a nM
Citation
 Gabr, M; Rehman, AU; Chen, HF Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling. ACS Med Chem Lett 11:1759-1765 (2020) [PubMed]  Article 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM31592
Synonyms:
PF-2545920 | US9138494, MP-10 | substituted pyrazole, 9
Type:
Small organic molecule
Emp. Form.:
C25H20N4O
Mol. Mass.:
392.4525
SMILES:
Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1
Structure:
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