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Target
Leukotriene B4 receptor 2
Ligand
BDBM50561365
Substrate
n/a
Meas. Tech.
ChEMBL_2074956 (CHEMBL4730490)
EC50
48±n/a nM
Citation
 Hernandez-Olmos, V; Heering, J; Planz, V; Liu, T; Kaps, A; Rajkumar, R; Gramzow, M; Kaiser, A; Schubert-Zsilavecz, M; Parnham, MJ; Windbergs, M; Steinhilber, D; Proschak, E First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters. J Med Chem 63:11548-11572 (2020) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 2
Synonyms:
BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37964.86
Organism:
Homo sapiens (Human)
Description:
Leukotriene 2 0 HUMAN::Q9NPC1
Residue:
358
Sequence:
MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
Inhibitor
Name:
BDBM50561365
Synonyms:
CHEMBL4785658
Type:
Small organic molecule
Emp. Form.:
C25H24FNO3
Mol. Mass.:
405.4614
SMILES:
CCCCC(=O)N(Cc1ccc(cc1F)-c1ccccc1C(O)=O)c1ccccc1
Structure:
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