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Target
N-arachidonyl glycine receptor
Ligand
BDBM50561705
Substrate
n/a
Meas. Tech.
ChEMBL_2075765 (CHEMBL4731299)
EC50
454±n/a nM
Citation
 Schoeder, CT; Mahardhika, AB; Drabczy?ska, A; Kie?-Kononowicz, K; Müller, CE Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18. ACS Med Chem Lett 11:2024-2031 (2020) [PubMed]  Article 
Target
Name:
N-arachidonyl glycine receptor
Synonyms:
G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor
Type:
PROTEIN
Mol. Mass.:
38150.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107601
Residue:
331
Sequence:
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
  
Inhibitor
Name:
BDBM50561705
Synonyms:
CHEMBL4758188
Type:
Small organic molecule
Emp. Form.:
C21H24N6O2
Mol. Mass.:
392.4543
SMILES:
Cn1c2nc3N(CCc4c[nH]c5ccccc45)CCCCn3c2c(=O)n(C)c1=O
Structure:
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