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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50126020
Substrate
n/a
Meas. Tech.
ChEBML_153884
IC50
20±n/a nM
Citation
 Santini, C; Berger, GD; Han, W; Mosley, R; MacNaul, K; Berger, J; Doebber, T; Wu, M; Moller, DE; Tolman, RL; Sahoo, SP Phenylacetic acid derivatives as hPPAR agonists. Bioorg Med Chem Lett 13:1277-80 (2003) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50126020
Synonyms:
CHEMBL25710 | {3-Chloro-4-[3-(3-hydroxy-4-propionyl-2-propyl-phenoxy)-propylsulfanyl]-phenyl}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C23H27ClO5S
Mol. Mass.:
450.975
SMILES:
CCCc1c(O)c(ccc1OCCCSc1ccc(CC(O)=O)cc1Cl)C(=O)CC
Structure:
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