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Target
D(2) dopamine receptor
Ligand
BDBM50318633
Substrate
n/a
Meas. Tech.
ChEMBL_2080340 (CHEMBL4736131)
Ki
997±n/a nM
Citation
 Vanda, D; Canale, V; Chaumont-Dubel, S; Kurczab, R; Sata?a, G; Koczurkiewicz-Adamczyk, P; Krawczyk, M; Pietru?, W; Blicharz, K; P?kala, E; Bojarski, AJ; Popik, P; Marin, P; Soural, M; Zajdel, P Imidazopyridine-Based 5-HT J Med Chem 64:1180-1196 (2021) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50318633
Synonyms:
3-benzenesulfonyl-8-piperazin-1-ylquinoline | CHEMBL1083390 | SB-742457
Type:
Small organic molecule
Emp. Form.:
C19H19N3O2S
Mol. Mass.:
353.438
SMILES:
O=S(=O)(c1ccccc1)c1cnc2c(cccc2c1)N1CCNCC1
Structure:
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