Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50562766
Substrate
n/a
Meas. Tech.
ChEMBL_2080392 (CHEMBL4736183)
Ki
970±n/a nM
Citation
 Qian, M; Ricarte, A; Wouters, E; Dalton, JAR; Risseeuw, MDP; Giraldo, J; Van Calenbergh, S Discovery of a true bivalent dopamine D Eur J Med Chem 212:0 (2021) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50562766
Synonyms:
CHEMBL4794870
Type:
Small organic molecule
Emp. Form.:
C32H36N2O2
Mol. Mass.:
480.6404
SMILES:
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCC#C)cc1)C1Cc2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: