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Target
N-formyl peptide receptor 2
Ligand
BDBM50563096
Substrate
n/a
Meas. Tech.
ChEMBL_2081556 (CHEMBL4737347)
EC50
0.250000±n/a nM
Citation
 Maciuszek, M; Ortega-Gomez, A; Maas, SL; Perretti, M; Merritt, A; Soehnlein, O; Chapman, TM Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation. Eur J Med Chem 214:0 (2021) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM50563096
Synonyms:
CHEMBL4794375
Type:
Small organic molecule
Emp. Form.:
C18H19FN2O3
Mol. Mass.:
330.3535
SMILES:
COc1ccc(cc1)[C@@H]1COC[C@@H]1NC(=O)Nc1ccc(F)cc1 |r|
Structure:
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