Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50127508
Substrate
n/a
Meas. Tech.
ChEMBL_200838 (CHEMBL807048)
IC50
53±n/a nM
Citation
 Prasad, V; Birzin, ET; McVaugh, CT; Van Rijn, RD; Rohrer, SP; Chicchi, G; Underwood, DJ; Thornton, ER; Smith, AB; Hirschmann, R Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents. J Med Chem 46:1858-69 (2003) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50127508
Synonyms:
5-(((2R,3R,4S,5R,6R)-5-((1H-imidazol-5-yl)methoxy)-6-(2-(1H-indol-3-yl)ethoxy)-4-(benzyloxy)-3-(pyridin-3-ylmethoxy)tetrahydro-2H-pyran-2-yl)methoxy)pentan-1-amine | 5-[4-Benzyloxy-5-(1H-imidazol-4-ylmethoxy)-6-[2-(1H-indol-3-yl)-ethoxy]-3-(pyridin-3-ylmethoxy)-tetrahydro-pyran-2-ylmethoxy]-pentylamine | CHEMBL54832
Type:
Small organic molecule
Emp. Form.:
C38H47N5O6
Mol. Mass.:
669.8097
SMILES:
NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@H](OCc2cnc[nH]2)[C@@H](OCc2ccccc2)[C@@H]1OCc1cccnc1
Structure:
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