Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50127869
Substrate
n/a
Meas. Tech.
ChEBML_162516
IC50
2200±n/a nM
Citation
 Yang, SW; Buivich, A; Chan, TM; Smith, M; Lachowicz, J; Pomponi, SA; Wright, AE; Mierzwa, R; Patel, M; Gullo, V; Chu, M A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp. Bioorg Med Chem Lett 13:1791-4 (2003) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50127869
Synonyms:
CHEMBL299307 | Sterol sulfate
Type:
Small organic molecule
Emp. Form.:
C30H52O10S2
Mol. Mass.:
636.859
SMILES:
C[C@H](C(O)C(O)C(C)C(C)(C)C)C1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OS([O-])(=O)=O)[C@@H](C[C@]4(C)[C@@]3(C)CC[C@]12C)OS([O-])(=O)=O
Structure:
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