Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 1
Ligand
BDBM50565179
Substrate
n/a
Meas. Tech.
ChEMBL_2090965 (CHEMBL4772228)
IC50
0.100000±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 1
Synonyms:
G-protein coupled receptor 147 | Gpr147 | NPFF1_RAT | Neuropeptide FF receptor 1 | Npff1 | Npffr1 | RFamide-related peptide receptor OT7T022
Type:
PROTEIN
Mol. Mass.:
48338.68
Organism:
Rattus norvegicus
Description:
ChEMBL_10681
Residue:
432
Sequence:
MEAEPSQPPNGSWPLGQNGSDVETSMATSLTFSSYYQHSSPVAAMFIAAYVLIFLLCMVGNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLTVTREEHHFMLDARNRSYPLYSCWEAWPEKGMRKVYTAVLFAHIYLVPLALIVVMYVRIARKLCQAPGPARDTEEAVAEGGRTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLIDYGELSELQLHLLSVYAFPLAHWLAFFHSSANPIIYGYFNENFRRGFQAAFRAQLCWPPWAAHKQAYSERPNRLLRRRVVVDVQPSDSGLPSESGPSSGVPGPGRLPLRNGRVAHQDGPGEGPGCNHMPLTIPAWNI
  
Inhibitor
Name:
BDBM50565179
Synonyms:
CHEMBL4782986
Type:
Small organic molecule
Emp. Form.:
C30H40N8O4
Mol. Mass.:
576.6898
SMILES:
NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O |r|
Structure:
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