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Target
Sentrin-specific protease 5
Ligand
BDBM50565367
Substrate
n/a
Meas. Tech.
ChEMBL_2091572 (CHEMBL4772835)
IC50
22300±n/a nM
Citation
 Wang, Z; Liu, Y; Zhang, J; Ullah, S; Kang, N; Zhao, Y; Zhou, H Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family. Eur J Med Chem 204:0 (2020) [PubMed]  Article 
Target
Name:
Sentrin-specific protease 5
Synonyms:
3.4.22.- | SENP5 | SENP5_HUMAN | Sentrin-specific protease 5 | Sentrin/SUMO-specific protease SENP5
Type:
PROTEIN
Mol. Mass.:
86736.43
Organism:
Homo sapiens
Description:
ChEMBL_120285
Residue:
755
Sequence:
MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGRKKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLKAVTDFPSNSALGQANGHRPRTDPQPSDFPMKFNGESQSPGESGTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIRFRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPSCRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADTSVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD
  
Inhibitor
Name:
BDBM50565367
Synonyms:
CHEMBL4788955
Type:
Small organic molecule
Emp. Form.:
C30H25N3O3S
Mol. Mass.:
507.603
SMILES:
Nc1cccc(c1)C(=O)Nc1cccc(CNC(=O)c2sc3ccccc3c2OCc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: