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Target
Cyclin-dependent kinase 1
Ligand
BDBM50132151
Substrate
n/a
Meas. Tech.
ChEBML_50325
IC50
>10000±n/a nM
Citation
 Furet, P; Bold, G; Hofmann, F; Manley, P; Meyer, T; Altmann, KH Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching. Bioorg Med Chem Lett 13:2967-71 (2003) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50132151
Synonyms:
CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-ylmethyl)-amino]-benzamide | N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benzamide | N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
Type:
Small organic molecule
Emp. Form.:
C19H16ClN3O
Mol. Mass.:
337.803
SMILES:
Clc1ccc(NC(=O)c2ccccc2NCc2ccncc2)cc1
Structure:
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