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Target
Inositol-trisphosphate 3-kinase A
Ligand
BDBM50132162
Substrate
n/a
Meas. Tech.
ChEBML_90112
IC50
27400±n/a nM
Citation
 Kwon, YU; Im, J; Choi, G; Kim, YS; Choi, KY; Chung, SK Synthesis of three enantiomeric pairs of scyllo-inositol phosphate and molecular interactions between all possible regioisomers of scyllo-inositol phosphate and inositol 1,4,5-trisphosphate 3-kinase. Bioorg Med Chem Lett 13:2981-4 (2003) [PubMed]  Article 
Target
Name:
Inositol-trisphosphate 3-kinase A
Synonyms:
IP3KA_RAT | Itpka
Type:
PROTEIN
Mol. Mass.:
50877.10
Organism:
Rattus norvegicus
Description:
ChEMBL_90112
Residue:
459
Sequence:
MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER
  
Inhibitor
Name:
BDBM50132162
Synonyms:
CHEMBL3349689 | Phosphoric acid mono-(2,3,4-trihydroxy-5,6-bis-phosphonooxy-cyclohexyl) ester
Type:
Small organic molecule
Emp. Form.:
C6H15O15P3
Mol. Mass.:
420.0956
SMILES:
O[C@@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: