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Target
Delta-type opioid receptor
Ligand
BDBM50568640
Substrate
n/a
Meas. Tech.
ChEMBL_2106124 (CHEMBL4814799)
Ki
63096±n/a nM
Citation
 Creed, SM; Gutridge, AM; Argade, MD; Hennessy, MR; Friesen, JB; Pauli, GF; van Rijn, RM; Riley, AP Isolation and Pharmacological Characterization of Six Opioidergic  J Nat Prod 84:71-80 (2021) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50568640
Synonyms:
CHEMBL4874877
Type:
Small organic molecule
Emp. Form.:
C23H26N2O4
Mol. Mass.:
394.4635
SMILES:
[H][C@@]12C[C@@]3([H])C(CN1CC[C@@]1(C2=Nc2ccccc12)[C@]3(COC(C)=O)C(=O)OC)=CC |r,t:13,TLB:29:5:2:10.11.19,18:10:2:7.5.6,12:11:2:7.5.6,20:19:2:7.5.6,THB:25:19:2:7.5.6,8:7:2:10.11.19,9:10:2:7.5.6,6:7:11:2.19.3|
Structure:
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